"Sumpter" Natural Recordings by Native Speakers
A summer.
The sumpter horse, often with a sedan chair, was a traditional means of conveying the wealthy ladies of London through the city streets.
In Beatrix Potter's Swallowtail Leonie', a sumpter was being reloaded by a groom at the kitchen window door of the Brooker's house.
The herbalist sent the herbs home in a big sumpter box.
If there were any jars left they were taken back to the pharmacy in the sumpter.
A sumpter horse used to be kept in town to cart garbage around
Summonses refer to written requests or orders issued by a court or authorized individual to appear before a court or tribunal as a defendant or witness in a legal proceeding. They are often issued in cases where a person has been accused of a crime or is required to provide testimony.
Sumner can refer to:<br><br>1. Sumner (unit) - a unit of time equal to 60 seconds.<br>2. Sumner (name) - a surname of English and Scottish origin.<br>3. Sumner (department store) - a now-defunct American department store chain.<br>4. Sumner County: <br> - Sumner County, Kansas, USA<br> - Sumner County, Tennessee, USA<br> - Sumner County, Utah, USA<br><br>A notable person:<br>- Charles Sumner (1811–1874), American politician and abolitionist.<br>- John Sumner (1904-1990), English footballer.<br>- John Bird Sumner (1780-1862), English churchman and Archbishop of Canterbury.<br>- Langston Hughes's poem "Sumner" was praising him.
Sumo is a style of professional wrestling or sport from Japan that originated in the 16th century. It is traditionally performed in a circular ring called a "dohyo" by two or more wrestlers, known as "rikishi", who are trying to force their opponent out of the ring or make them touch the ground. The sport is known for its strong cultural and spiritual significance in Japan, with the largest sumo tournament, called the "Honbasho", held annually in Tokyo.
A sumoist is a slang term that refers to someone who is obsessed with or excessively enthusiastic about the sport of sumo wrestling.
The word "sumoylate" is a verb that means to modify or regulate the activity of a protein by adding a small ubiquitin-like modifier, specifically a small ubiquitin-like modifier protein, or SUMO.
Sumoylation is a post-translational modification (PTM) of proteins, where a small ubiquitin-like modifier protein (SUMO) is covalently attached to a lysine residue on a target protein. This process is reversible, involving an isopeptidase called SENP (Sentrin/SUMO-specific protease).<br><br>During sumoylation, a SUMO protein molecule (approx. 100 amino acids long) is transferred to a lysine side chain of the target protein through an isopeptide bond. The attachment of SUMO to a protein can have various functions, including:<br><br>1. <strong>Regulation of protein activity</strong>: Sumoylation can activate or inhibit the activity of a protein. For example, sumoylation can inhibit the activity of certain transcription factors or regulate the activity of DNA repair enzymes.<br>2. <strong>Protein-protein interactions</strong>: Sumoylation can facilitate or disrupt protein-protein interactions by modifying the binding properties of a protein. Sumoylation can also create a binding site for other proteins, which can then recognize the sumoylated protein.<br>3. <strong>Protein localization and targeting</strong>: Sumoylation can affect the localization of a protein within the cell. For example, sumoylation can target a protein to a specific subcellular compartment or membrane.<br>4. <strong>Cellular responses to stress</strong>: Sumoylation can play a role in cellular responses to stress, such as the heat shock response or DNA damage.<br>5. <strong>Regulation of gene expression</strong>: Sumoylation can influence the expression of genes by modifying the activity of transcription factors or other regulators of gene expression.<br><br>Sumoylation has been implicated in many biological processes, including:<br><br> Development and differentiation<br> Cell growth and proliferation<br> Response to stress and DNA damage<br> Viral infection and cancer<br> Neurological diseases<br><br>Dysregulation of sumoylation has been linked to various diseases, including cancer, neurodegenerative disorders, and developmental disorders.
A depression in the ground that collects a flood of water when a sewer or other system is stopped up.
Having to do with luxurious or elegant living; concerned with the regulation of luxury, especially in dress and food.<br><br>Example: "Sumptuary laws were introduced to regulate the luxurious attire of the nobility."<br><br>Synonyms: luxurious, opulent, extravagant.
Extravagance or luxuriousness, typically in a way that is considered excessive or ostentatious.
The quality or state of being excessively luxurious, elegant, or refined, characterized by a rich and elaborate style, often to an excessive or ostentatious degree.
Sunny and warm, typically to an excessive degree, especially in a way that causes discomfort or dryness.