"Sulfadoxine" Pronounce,Meaning And Examples

"Sulfadoxine" Natural Recordings by Native Speakers

Sulfadoxine

"Sulfadoxine" Meaning

Sulfadoxine is a sulfonamide antibiotic that is used in combination with pyrimethamine to treat malaria, particularly in areas where resistance to chloroquine is prevalent. It works by inhibiting the bacterial enzyme dihydropteroate synthase (DHPS), which is essential for the synthesis of tetrahydrofolic acid. This antimicrobial action kills the malaria parasite and other susceptible bacteria.

In combination with pyrimethamine, sulfadoxine is used to:

1. Treat uncomplicated malaria caused by Plasmodium falciparum.
2. Prevent malaria in travelers to areas where the disease is endemic.
3. Treat toxoplasmosis, a parasitic infection caused by Toxoplasma gondii.

Sulfadoxine can also be used as a prophylactic measure against malaria in pregnant women, especially in areas where the disease is common.

When taken with pyrimethamine, sulfadoxine is often referred to as SP (sulfadoxine-pyrimethamine), a widely used antimalarial medication.

"Sulfadoxine" Examples

Definition:

Sulphadoxine is an antibacterial agent and part of the sulfonamide group.

Usage Examples:

1. Medical Context:

Sulphadoxine is often used with pyrimethamine for the treatment and prophylaxis of the malaria caused by Plasmodium falciparum in combination with other drugs.

2. Research Setting:

Studies have shown that sulphadoxine-pyrimethamine combination significantly reduces morbidity and mortality from malaria infections, making it a critical component in malaria treatments in endemic regions.

3. Scientific Abstract:

This clinical trial assesses the efficacy of sulphadoxine and pyrimethamine compared to chloroquine for the prevention of malaria among school children in areas without widespread chloroquine resistance.

4. Pharmaceutical Report:

Our quarterly sales report indicates a higher demand for paediatric dispersions containing sulphadoxine and pyrimethamine, signifying an increased focus on affordable antimalarial treatment options for children under 5.

5. Public Health Initiative:

As part of our initiative to combat malaria in the city, we will be providing free sulphadoxine-pyrimethamine treatments to all residents from malaria-prone districts effective next quarter.

"Sulfadoxine" Similar Words

Sulci

1. SULCI (plural noun) refers to a deep fold or cleft in the surface of the earth or the brain. In the context of the brain, it is a long, narrow groove or fold in the surface of the cerebral hemisphere. Sulci are of various sizes and can vary in depth and width. 2. It could also refer to a deep, narrow incision or gash in some material, such as wood or stone.

Sulciform

Having a groove or furrow, typically on the upper surface of an object, and often resembling a sulcus (a long, narrow furrow).

Sulcus

A sulcus is a long narrow groove or fissure in the surface of a bone, an organ, or a leaf. It can also refer to a fissure in the brain or a deepening of the forehead that is persistent from birth, often in the space between the eyebrows.

Suleiman

"Suleiman" is the English name for the Islamic prophet known as Suleyman (also spelled as Sulayman) in the Quran. He was the third king of the Islamic kingdom of Hejaz. In Islamic tradition, Suleiman was a prophet, a wise and powerful king, and a military leader who ruled over the kingdoms of David and Solomon. He is believed to have ruled over a vast empire that included modern-day Israel, Palestine, Jordan, parts of Lebanon, and parts of Syria. Suleiman is also the name of a chemical element with the symbol Su and atomic number 106, which is a synthetic element that is derived from the name of the eleventh-century king. In addition, Suleiman can refer to the 10th Sultan of the Ottoman Empire, Suleiman the Magnificent, who ruled from 1520 to 1566. He is known for his military conquests, administrative reforms, and cultural achievements. Overall, the name Suleiman has a rich historical and cultural significance in the Middle East and other parts of the world.

Sulfa

Sulfa refers to a type of medication, specifically a class of antimicrobials that contain sulfonamide or sulfanilamide compounds. They are used to treat various infections, often bacterial, by inhibiting the synthesis of folic acid, which is necessary for the growth and reproduction of bacteria. The term "sulfa" is also sometimes used informally to refer to sulfonamide antibiotic medications, which may include: 1. Sulfamethoxazole (SMX) 2. Sulfadiazine (SDZ) 3. Sulfamethazine (SMZ) 4. Sulfamethoxazole/trimethoprim (SMX-TMP) 5. And others Sulfa medications have been widely used in human medicine for many years to treat various types of bacterial infections, including those caused by streptococci, staphylococci, and enterococci.

Sulfacetamide

Sulfacetamide is a topical or oral antibacterial agent used in the treatment of ocular infections, such as conjunctivitis. It belongs to the sulfonamide class of drugs and works by inhibiting the growth of bacteria that cause infections. Sulfacetamide can also be used as an eye wash or drops to treat eye infections in dogs and cats.

Sulfactant

Sulfactant: A type of surfactant that reduces the surface tension between water surfaces and the air. Specifically, it is a substance produced by the lungs and lining the alveoli, which helps to reduce the surface tension within the lungs and make breathing easier.

Sulfadiazine

Sulphadiazine is a sulfonamide antibiotic used in treating bacterial infections, including urinary tract infections, septicaemia, and meningitis. It typically comes in combination with pyrimethamine, known as sulfadoxine.

Sulfamethazine

Sulfamethazine (also known as sulfadiazine or sulfamethazine sodium) is a sulfonamide antibiotic that was commonly used in veterinary medicine. It was used to treat a variety of bacterial infections in animals. As an antibiotic, sulfamethazine works by inhibiting the growth and reproduction of bacteria by interfering with the synthesis of folic acid, which is necessary for bacterial cell growth. It was often used to treat a range of infections, including respiratory tract infections, urinary tract infections, and skin infections in animals. However, it is no longer commonly used as an antibiotic in humans or animals due to the availability of more effective and safer alternatives. It is also contraindicated in some individuals due to the potential for adverse effects.

Sulfamethoxazole

Sulfamethoxazole is a medication used to treat certain bacterial infections. It belongs to a class of medications called sulfonamides, which are antibiotics that work by stopping the growth of bacteria. Sulfamethoxazole is often used in combination with other antibiotics, such as trimethoprim, to treat a wide range of bacterial infections, including urinary tract infections, respiratory tract infections, and skin infections. It is available by prescription only and should only be used under the guidance of a healthcare professional.

Sulfamic

Sulfamic acid is a weak organic acid with the molecular formula (H3NSO3) or H3N+SO3-. It is a colorless, syrupy, and odorless liquid that is highly soluble in water and alcohol but has little or no solubility in ether and other non-polar solvents.

Sulfamide

The word "sulfamide" refers to a derivative of sulfamic acid, a compound used in chemical synthesis, particularly in the production of certain drugs and pesticides. Sulfamides are a class of compounds that contain the sulfonamide group (-SO2NH2) and are known for their antimicrobial properties. In a broader sense, the term "sulfamide" can also refer to any compound that contains a sulfonamide group, even if it is not a derivative of sulfamic acid. Some examples of sulfamides include sulfamethoxazole, a drug used to treat certain infections, and sulfachlorpyridazine, an antibacterial agent used in agriculture. In chemistry, the term "sulfamide" is often used to describe a wide range of compounds that contain a sulfonamide group, regardless of their specific chemical structure or function.

Sulfanilamide

Sulfanilamide is a type of organic compound that is derived from sulfanilic acid. It's often used in the production of other medicines, dyes, and other chemicals. In the 1930s, sulfanilamide was the first commercially available form of sulfonamide, a class of antimicrobial drugs. However, early formulations of sulfanilamide were not very effective and had some serious side effects. One notable incident involving sulfanilamide was the Sulfanilamide disaster, which occurred in 1937. The company Eli Lilly released a liquid form of sulfanilamide that used diethylene glycol (DEG), a toxic substance, as a solvent. Many people in the United States died from kidney damage caused by the contaminated medicine. This event led to stricter regulations on the approval of new medicines in the US.

Sulfapyridine

Sulfapyridine is a sulfonamide antibacterial medication used to treat bacterial infections, such as those caused by E. coli, Shigella, and Proteus. It was one of the first antibiotics developed and was introduced in the 1930s.

Sulfasalazine

Sulfasalazine: A type of nonsteroidal anti-inflammatory drug (NSAID) that is used to treat rheumatoid arthritis and severe ulcerative colitis. It works by reducing inflammation and suppressing the production of folic acid antagonists, which helps to alleviate symptoms such as pain, stiffness, and swelling in the joints and digestive tract.

Sulfatase

Sulfatase refers to a group of enzymes that catalyze the hydrolysis of sulfate esters, releasing sulfate ions and an alcohol. These enzymes are involved in the breakdown of sulfated compounds, such as steroid sulfates, glycosaminoglycans, and esterified sulfate ions in various biological processes, including lipid metabolism, drug metabolism, and disease processes like morphine addiction. More specifically, sulfatases are a class of hydrolases (enzymes that hydrolyze chemical bonds) that specifically hydrolyze the sulfate ester bond, splitting the molecule into its components. They are found in a wide range of organisms, including bacteria, archaea, plants, and animals. Sulfatases play critical roles in various biological processes, such as: 1. Phospholipid metabolism: Sulfatases hydrolyze sulfated glycosphingolipids and sulfoglycolipids, which are essential for cell signaling and membrane structure. 2. Drug metabolism: Sulfatases are involved in the metabolism of sulfate conjugated drugs, such as morphine and fentanyl, making them more water-soluble and eventually excretable. 3. Reproductive processes: Sulfatases are essential for the formation and function of steroid hormones, such as estrone sulfate, which regulates reproductive development and function. 4. Cancer and disease: Abnormal sulfatase activities have been implicated in various diseases, including cancer, genetic disorders, and cardiovascular diseases. In summary, sulfatases are enzymes that play critical roles in various biological processes, including the breakdown of sulfated compounds, lipid metabolism, and disease processes, demonstrating the importance of these enzymes in maintaining normal physiological function and preventing disease.