"Vedolizumab" Pronounce,Meaning And Examples

"Vedolizumab" Natural Recordings by Native Speakers

Vedolizumab

"Vedolizumab" Meaning

Vedolizumab is a medication used to treat inflammatory bowel disease (IBD), specifically ulcerative colitis (UC) and Crohn's disease (CD). It belongs to a class of medications called monoclonal antibodies, which are designed to target specific molecules in the body that contribute to inflammation and immune system dysregulation.

Vedolizumab specifically targets the alpha4beta7 integrin molecules on the surface of immune cells, which are involved in the adhesion and migration of these cells into the gut lining, where they can contribute to inflammation. By binding to these integrins, vedolizumab blocks the migration of immune cells into the gut, thereby reducing inflammation and promoting healing.

Vedolizumab is administered through intravenous (IV) infusion every 8 weeks. It is typically used in combination with other therapies, such as aminosalicylates, corticosteroids, and immunosuppressives, to manage IBD symptoms.

Common side effects of vedolizumab include headache, fatigue, nausea, diarrhea, and djarrhea. Rare but serious side effects may include hypersensitivity reactions, neurological problems, and increased risk of infections.

In the context of fertility and pregnancy, there is limited data on the use of vedolizumab in pregnant women, and it is generally recommended to avoid its use during pregnancy if possible. Women of childbearing potential should be advised to use effective contraception while taking vedolizumab.

Overall, vedolizumab is a targeted therapy that has shown to be effective in reducing inflammation and managing symptoms of IBD; however, it requires careful monitoring and management due to the potential for side effects.

"Vedolizumab" Examples

Vedolizumab Usage Examples

1. Medical Context

Vedolizumab is used to:
> Patients with moderately to severely active Crohn's disease (CD) or ulcerative colitis (UC) with an inadequate response or loss of response to prior therapies are candidates for vedolizumab treatment.

2. Pharmaceutical Product Description

The pharmaceutical multinational company Takeda Pharmaceutical uses vedolizumab:
> Takeda Pharmaceutical's ENTYVIO (vedolizumab injection) is the first and only integrin receptor antagonist monoclonal antibody approved to treat adult patients with moderately to severely active Ulcerative Colitis.

3. Research Study Reference

A medical research study references vedolizumab:
> In a multicenter, phase 2/3, randomized, double-blind, placebo-controlled, dose-escalation clinical trial, vedolizumab (4.5 mg/kg intravenously) was administered to patients suffering from ulcerative colitis.

4. Treatment Method

A clinical nurse describes how to administer vedolizumab:
> Closely monitor patients at least 1 hour after administration of vedolizumab, which can induce severe infusion-related reactions (IRRs) such as severe allergic reactions, cardiovascular events, and changes in heart rate and blood pressure.

5. Clinical Side Effects

potential adverse effects of vedolizumab mentioned in medical literature include:
> The following were observed: viral gastroenteritis, nasopharyngitis, upper respiratory tract infection, bronchitis, periodontal abscess.

"Vedolizumab" Similar Words

Vedant

Vedanta

Vedanta (Sanskrit: वेदान्त) refers to the philosophical and spiritual tradition that originated from the Upanishads, the Hindu scriptures. The term "Vedanta" literally means "the end of the Vedas" or the ultimate reality. It is often referred to as the eastern equivalent of Western philosophy, specifically, the Term combines "Vedas" meaning knowledge, or conventual meaning, and "anta" meaning the end. Vedanta describes the ultimate reality as Brahman, a supreme unchanging, all-knowing, universal principle or consciousness that governs the universe and underlies the human soul or Atman. The tradition emphasizes a visionary process in which one individually realises the meaning of these teachings of the Upanishads and transforms the world as a result of what has been learned.

Vedantic

The term "Vedantic" refers to the philosophical and spiritual teachings of the Vedas, which are ancient Sanskrit texts of Hinduism. The Vedanta is a school of thought that focuses on the ultimate nature of reality, consciousness, and the self. It is a system of philosophy that seeks to understand and realize the ultimate truth or Brahman, which is seen as the unchanging, all-pervading essence of the universe. In Vedantic philosophy, the ultimate goal is to attain liberation or moksha, which is the realization of one's true nature as the essence of Brahman. This is achieved through the practice of yoga, dhyana (meditation), and other spiritual disciplines, as well as through the study of the Vedas and other sacred texts. Vedantic philosophy emphasizes the following key concepts: The ultimate reality is Brahman, which is beyond human comprehension and experience. The individual self (jiva) is a spark of Brahman and is ultimately not separate from it. The universe is an illusion (maya) and is not ultimately real. The ultimate goal is to realize one's true nature as Brahman through self-inquiry and the practice of yoga and meditation. In the context of spiritual growth and self-realization, the term "Vedantic" can also refer to the practice of living in accordance with the principles and values revealed in the Vedas, such as non-violence, compassion, and self-discipline.

Vedantist

A Vedantist is a follower of the Vedantist movement, a philosophical and spiritual tradition based on the teachings of the Upanishads, which are ancient Hindu scriptures. The name "Vedantist" is derived from the Sanskrit word "Vedanta", which means "the end of the Vedas". Vedantism is a philosophical school of thought that originated in ancient India and is based on the idea that the ultimate reality or the Absolute Truth is a unified, all-encompassing consciousness that underlies all existence. This consciousness is often referred to as Brahman. Vedantists believe in the concept of nondualism, which holds that the individual self (jiva) is not separate from the ultimate reality (Brahman), and that the distinction between them is only illusory. This philosophy emphasizes the importance of self-realization and the attainment of liberation (moksha) from the cycle of rebirth and death. In practical terms, Vedantism emphasizes the value of self-inquiry, meditation, and the cultivation of spiritual practices such as yoga and pranayama to achieve a deeper understanding of the self and the ultimate reality. It also stresses the importance of non-attachment, compassion, and selfless action in leading a moral and virtuous life.

Vedas

The Vedas (Sanskrit: वेद, Veda) are ancient Indian texts that form a part of Hinduism. They are considered to be the oldest and most sacred scriptures of Hinduism, and are a foundational text of Hindu and Indian philosophy. There are four Vedas: 1. The Rigveda (Rig-Veda): The oldest of the four Vedas, it is a collection of hymns and prayers to the gods. 2. The Yajurveda (Yaju-Veda): This Veda is concerned with rituals and the sacrificial rituals. 3. The Samaveda (Sama-Veda): This Veda is a collection of melodies and chants recited during the yajna or sacrifice. 4. The Atharvaveda (Atharva-Veda): This Veda is associated with magic, healing, and the concept of higher self. The Vedas are not just texts, but a way of life that has shaped Indian culture, philosophy, and spirituality. They contain insights and knowledge on various aspects of life, including spiritual growth, social and personal conduct, family life, wealth, and the self. In essence, the Vedas offer a holistic approach to understanding the universe, life, and our place within the universe. They continue to be studied and revered by millions of people around the world, seeking wisdom, insight, and spiritual guidance.

Vedic

Vedic refers to the ancient body of texts, rituals, and practices of ancient India, specifically those related to the Vedic period (1500 BCE - 500 BCE). The term "Vedic" comes from the Sanskrit word "Veda," which means "Knowledge" or "Wisdom." In a broader sense, Vedic often connotes ancient Indian wisdom, traditions, and spirituality, including: 1. The Vedas: The oldest and most sacred Hindu scriptures, comprising four collections of sacred hymns, prayers, and philosophical discussions. 2. Astrology: Vedic astrology, also known as Jyotish, emphasizes the connection between the positions of celestial bodies and human affairs. 3. Ayurveda: The traditional Indian system of medicine, which aims to prevent and treat diseases using natural remedies. 4. Yoga: Some forms of yoga, such as Hatha Yoga and Ashtanga Yoga, have their roots in ancient Vedic traditions. 5. Spirituality: Vedic thought emphasizes the connection between the individual self (Atman) and the universal Self (Brahman). Vedic wisdom is often associated with the following key principles: The cyclical nature of time and the interconnectedness of all things The concept of karma and the law of cause-and-effect The importance of rituals, ceremonies, and spiritual practices The pursuit of inner wisdom and self-realization (Atma-Gnosis) Overall, the term "Vedic" evokes a sense of ancient wisdom, tradition, and spiritual depth, reflecting the cultural and philosophical heritage of ancient India.

Vedism

Vedism refers to a set of ancient Indian Vedic rituals and philosophies described in the Vedas, which are the oldest and most sacred texts of Hinduism. The term is often used to describe the pre-Vedic and early Vedic period, which dates from approximately 1500 BCE to 700 BCE. Vedism encompasses a range of spiritual, philosophical, and ritual practices that were prevalent during this time. Some key features of Vedism include: 1. Polytheism: Worship of multiple gods and goddesses, each with distinct personalities and domains. 2. Animal sacrifice: The practice of offering animal sacrifices to appease the gods and ensure fertility, prosperity, and protection. 3. Fire worship: The reverence of fire as a purifying and sacred element. 4. Rituals and ceremonies: Complex and elaborate rituals, including the recitation of Vedic mantras and hymns, which were believed to have spiritual and cosmic significance. 5. Cosmology: A complex and dynamic view of the universe, with three main categories: heaven (the realm of the gods), the material world, and the underworld. Overall, Vedism is a significant part of the early history of Indian thought and culture, and its ideas and practices continue to influence Hinduism, Indian philosophy, and ritual practices to this day.

Vedist

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Veduta

"A veduta is a painting which depicts a bird's-eye view of a landscape or a cityscape, often executed with a particular emphasis on the horizon line. It is typically created from a high vantage point, attempting to capture the architecture and scenery in a comprehensive and detailed fashion. Although the term often connotes an elevated perspective, skies and figures below may or may not be dominated by a strong focus on the vantage point. Many vedute feature majestic grandeur and idyllic settings. Sometimes, vedute overlap in form with veduting."

Veer

Veer is an adjective that means: Nervous or excited, often in a fearful or apprehensive way (e.g. "The kid was veering wildly on the bicycle.") Turning or tending to turn away from the course of events (e.g. "The ship began to veer off course due to strong winds.") Lying or sloping at an angle, often away from a perpendicular or level plane (e.g. "The roof of the old house had a slight veer to it.") A male given name, derived from Sanskrit (e.g. Prince Veer Bewoor of India). It can also refer to a type of Brahmistor with elongated base and six hooks suitable for woman.

Veered

To veer is to turn suddenly or sharply to one side, often in a moving vehicle or in a direction of movement. Example: The car veered off the road and into the ditch.

Veering

Veers

To deviate or take a non-straight course; shift direction. Example: "The road veers north at the next intersection."

Vega

Vega is a reference to one of the brightest stars in the night sky, located in the constellation Lyra. It is significant not only for its brightness but also its importance in various fields. Vega is a showstopper in terms of astronomical information and is well-known for its distinctive characteristics. Astronomers and space navigators use it for orientation as it provides a reliable marker in the night sky. In terms of mythology, Vega has a story. It is named after a maternal figure in a Babylonian myth, possibly meaning a lady or a goddess. The name 'Vega' comes from Arabic, which contributed significantly to the naming of many stars in the sky. In many contexts, Vega signifies not only a bright celestial body but also has strong connections with the cultural and mythological realm. In modern times, Vega has significant importance in technology and navigation, serving as a major reference point. The above-stated points are just a few examples of how the significance and name of Vega have resulted from its several attributes making it a unique spectacle in the vast expanse of the universe.

Vegan

Vegan: A person who does not eat, use or wear anything that comes from animals.

Veganism

The word "veganism" refers to a diet, lifestyle, and philosophy that rejects the consumption of animal products, particularly in diet. Vegans do not eat meat, dairy, eggs, or any other product that comes from animals, including honey. Instead, they focus on consuming plant-based foods such as fruits, vegetables, grains, and legumes. Veganism is also an ideology that seeks to minimize harm to animals and the environment. Many vegans believe that animal exploitation and suffering in animal agriculture and other industries reinforce societal norms and values that justify harm and cruelty. The term "vegan" was coined in 1944 by Donald Watson, an English animal rights activist, from the first two syllables of the word "vegetarian." Since then, veganism has grown in popularity as a way to promote animal welfare, environmental sustainability, and human health. Vegans often choose this lifestyle for various reasons, including: Animal welfare: To avoid contributing to animal suffering, cruelty, and exploitation in industries like factory farming. Environmentalism: To reduce their carbon footprint, conserve natural resources, and protect ecosystems. Health: To promote better health, weight management, and well-being by following a plant-based diet. Ethics: To adopt a way of living that aligns with their values and promotes compassion, justice, and equality. Overall, veganism is a lifestyle that advocates for kindness, sustainability, and respect for all living beings and the planet.