"Tubulin" Pronounce,Meaning And Examples

"Tubulin" Natural Recordings by Native Speakers

Tubulin

"Tubulin" Meaning

Tubulin is a key protein component of microtubules, which are essential for the structure and movement of eukaryotic cells. Microtubules are dynamic, tubular structures composed of tubulin protein subunits that play a critical role in various cellular processes, including:

1. Cell division: Microtubules form the spindle fibers that separate chromosomes during cell division, ensuring accurate chromosome segregation.
2. Intracellular transport: Tubulin microtubules act as tracks for motor proteins (kinesin and dynein) to move organelles, vesicles, and other cellular components within the cell.
3. Cell shape and architecture: Microtubules provide structural support and maintain the shape of cells, particularly during cell growth and migration.
4. Cytoskeletal stability: Microtubules contribute to cellular stability and mechanical strength, helping cells to resist external forces and maintaining cell integrity.

Tubulin is a key player in these processes and is composed of two main forms: alpha-tubulin and beta-tubulin. These subunits assemble to form microtubules, which are stabilized by other microtubule-associated proteins.

"Tubulin" Examples

Usage Examples for the Word "Tubulin"

1. In Biological Context:

Tubulin is a key component of microtubules, which are involved in cell division. In many cells, microtubules form a mitotic spindle with astral microtubules. The mitotic spindle moves chromosomes, organizing them into a visible spire-like form called a "astral spindle" or "anastral spindle." During cell division, microtubules begin to shorten at their minus ends and reinforce the attachment of the kinetochore to microtubules attached to the Pole, as shown in [1].

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During cell division, microtubules composed of the protein tubulin shrink and unfurl to separate the duplicated chromosomes into daughter cells.

2. In Molecular Biology:

The discovery of tubulin as the primary protein of microtubules came in 1960 when Randall Hardy isolated it from porcine brain tissue. Tubulin works with GTP in a way that is somewhat similar to actin's association with ATP, and dimerization of tubulin subunits forms the microtubule filament.

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Tubulin is a globular protein that can extract from most eukaryotic cells. This is the most abundant protein found in microtubules.

3. In Neuroscience:

The microtubules consist of globular protein dimers composed of α-tubulin and β-tubulin. β-tubulin exists in lamins but does not undergo modifications equivalent to those in α-tubulin. Microtubule interactions with various proteins and other filaments are capable of inducing circumferential contractions. Circumferential contraction of the axial protein microtubules of a given filament can cause vesicles in the Golgi apparatus to move into the area in front of that dynamic +-end. Vesicles unfurling by a certain extent but not totally equidistant leaves bundled vesicles for posterior morphogenesis [31].

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Microtubules, produced from microtubulin sub-units, are dynamic, tubular structures within the cells.

4. In Reference High School Books (Science text):

Many efforts were made by scientists to make a model that can form microtubules composed of tubulin. This great actuality and concept works as the situation explained in high school book.

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Imagine one eukaryotic cell which has a

"Tubulin" Similar Words

Tubulation

Tubulation refers to the formation or connection of tubes, typically involving the growth of tubular structures, often associated with biological processes. It is used in various contexts such as anatomy (the formation of tubes or channels within a living organism), linguistics (the formation of tubular sounds in philology), and engineering (the creation of tubes or pipes for transportation or fluid dynamics).

Tubulature

Tubule

Tubules

Tubulibranchian

The term "Tubulibranchian" refers to a subclass of marine gastropod mollusks, commonly known as sea hares, cone snails, or sea butterflies. The name is derived from "tubuli" (Latin for "little tubes") and "branchia" (Greek for "gills"), which refers to the presence of internal, tubular gills in these marine animals. These creatures are primarily found in tropical and subtropical oceans around the world. As a class of mollusk, they are generally slow-moving, often using their wings-like parapodia to glide through the water in a manner reminiscent of a butterfly (hence, "sea butterflies"). Notably, many species of sea hares are venomous; a few species of cone snails are well-known for their dangerous venom and are among the most venomous animals in the world. Tubulibranchians are important ecosystem components, participating in nutrient cycling through the consumption of algae and organic matter, and serving as hosts for various parasites and associations with marine animals, such as the sea hares' well-documented relationship with zooxanthellae, photosynthetic algae that symbiotically inhabit their bodies.

Tubulicole

Tubulidentata

Tubulidentate

Tubulipore

Tubulisation

Tubulization

Tubuloalveolar

Tubulogenesis

Tubuloglomerular

The term "tubuloglomerular" refers to a structure or process involving the association or interaction between tubules and the glomeruli in the kidney. In the context of renal physiology, the tubuloglomerular feedback mechanism is a critical regulatory process that helps to control the rate of glomerular filtration rate (GFR). This feedback mechanism is primarily mediated by the macula densa cells located at the junction between the thick ascending limb of the loop of Henle and the distal convoluted tubule. Here's how it works: 1. The macula densa cells in the distal convoluted tubule detect the concentration of ions and other substances in the filtrate passing through them, which reflects the GFR. 2. If the GFR increases, the macula densa cells detect an increase in sodium chloride ion concentration and other waste products. 3. In response, the macula densa cells signal the juxtaglomerular cells in the afferent arteriole, which then release renin, an enzyme that triggers a cascade of reactions leading to increased aldosterone production by the adrenal cortex. 4. Feedback inhibition also occurs when the macula densa cells detect a decrease in GFR, leading to decreased renin release and reduced aldosterone production, which maintains a stable GFR. This tubuloglomerular feedback feedback loop fine-tunes the GFR according to the body's needs, ensuring adequate filtration while preventing excessive fluid loss or vascular strain.