"Streptogramin" Pronounce,Meaning And Examples

"Streptogramin" Natural Recordings by Native Speakers

Streptogramin
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"Streptogramin" Meaning

Streptogramin refers to a class of antibacterial drugs that inhibit protein synthesis by binding to the ribosome. They are characterized by a unique mechanism of action, where they bind to both the 50S subunit of the bacterial ribosome and the ribosomal protein L16, leading to inhibition of protein synthesis.

"Streptogramin" Examples

Usage Examples for Streptogramin


1. Antibiotic Class

Streptogramin B is a component of the streptogramin antibiotics, a class of antibiotics that have been refined for medical use. The use of streptogramins such as quinupristin/dalfopristin is recommended for serious infections caused by Gram-positive bacteria that have been resistant to other antibiotics.

2. Medical Application

Streptogramins work by inhibiting protein synthesis, which is essential for bacterial survival. They are particularly effective against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant enterococci (VRE).

3. Synthetic Pathway

Streptogramins are produced by the bacteria Actinoplanes species and Streptogramin B can be synthesized chemically or biologically. The isolation and large-scale fermentation of these compounds are critical steps in producing effective antibiotics for medical use.

4. Clinical Research

Research into streptogramins highlights their potential in treating infections caused by bacteria that are resistant to common antibiotics. Studies focused on the pharmacodynamics and pharmacokinetics of these compounds inform treatment regimens that ensure the most effective dosage without adverse effects.

5. Mechanism of Action

The streptogramin antibiotic combination quinupristin and dalfopristin works by inhibiting the bacterial 50S subunit of ribosomes, which are essential to protein synthesis in bacteria. This mechanism of action contributes to the drugs' efficacy against resistant bacterial strains.

"Streptogramin" Similar Words

Streptobacillus

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The term "streptobacillus" refers to a genus of Gram-negative, rod-shaped bacteria that belong to the family Pasteurellaceae. The name "Streptobacillus" comes from the Greek words "streptos," meaning twisted or in a rope, and "bacillus," which means small staff or rod. These bacteria are typically found in a wide range of environments, including soil and water, and are often associated with small animals, such as rodents.

Streptocarpus

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Streptococcaceae

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The family Streptococcaceae is a family of Gram-positive, facultatively anaerobic cocci. It was previously a family in the order Lactobacillales, but it has been moved to the order Lactobacillales is no longer a valid taxonomic ranking, thus contributing to the status of Streptococcaceae as not validly published although it is widely used.

Streptococcal

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Relating to a type of bacterial infection caused by streptococci, a group of spherical, often chain-forming bacteria.

Streptococci

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Streptococcus

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Streptococcus: A type of Gram-positive, spherical bacteria that occurs in pairs (diplococci) or chains. It is a common cause of various infections, including strep throat, pneumonia, and skin infections.

Streptocyanine

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Streptodornase

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Streptodornase is a deoxyribonuclease enzyme produced by the bacterium Streptococcus pyogenes. It breaks down extracellular DNA (exDNA) that is subjected to severe environmental conditions, such as acidic or heat stress. This enzyme maintains a relatively constant and optimal pH in biofilms composed of exDNA.

Streptokinase

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Streptolysin

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Streptomyces

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Streptomyces refers to a genus of a large and diverse group of Gram-positive, soil-dwelling bacteria. They are known for producing antibiotics, producing pigments, and helping in the decomposition of organic matter.

Streptomycetaceae

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Streptomycete

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Streptomycetes

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Streptomycetes are a group of Gram-positive, aerobic bacteria that are characterized by their filamentous vegetative cells and the presence of aerial hyphae that produce spores. They are one of the largest and most diverse genera of bacteria and are commonly found in soil.<br><br>Streptomycetes have several characteristics that distinguish them from other bacteria. They have a complex cell structure, with a long, branching vegetative cell that gives rise to aerial hyphae. These aerial hyphae are specialized to produce spores, which are allowed to disperse in the air and spread the bacteria to new areas.<br><br>Streptomycetes are of great interest in the field of medicine, as they are the source of a number of important antibiotics, including streptomycin, tetracycline, and gentamicin. They are also used in the production of vitamins and other compounds of biotechnological interest.<br><br>They are widely distributed in the world and are commonly found in soil, which contain around 140 species of streptomycetes. Streptomycetes can be disturbed by activities such as heavy use of chemical fertilizers, as this provides phosphorus in soil, causing problems to streptomycetes.

Streptomycin

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Streptomycineae

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The Streptomycetaceae is a family of Gram-positive, filamentous bacteria within the order Actinomycetales. They are a suborder within the phylum Actinobacteria.