"Sofosbuvir" Pronounce,Meaning And Examples

"Sofosbuvir" Natural Recordings by Native Speakers

Sofosbuvir

"Sofosbuvir" Meaning

Sofosbuvir is an antiviral medication used to treat hepatitis C, a viral infection that causes liver inflammation. It is a nucleotide analogue inhibitor (NAI) of the NS5B polymerase, a key enzyme in the replication of the hepatitis C virus (HCV).

Sofosbuvir works by blocking the replication of HCV, thereby reducing the amount of virus in the body and allowing the liver to heal. It is often used in combination with other medications, such as pegylated interferon and/or ribavirin, to enhance its effectiveness.

Sofosbuvir has been shown to be effective in treating both genotype 1 and genotype 3 HCV infections, and has a high barrier to the development of resistance. It is generally well-tolerated, with common side effects including headache, fatigue, and nausea.

"Sofosbuvir" Examples

Common Usage Examples of Sofosbuvir:

1. Medical Prescription

- Example Sentence
- "The doctor prescribed sofosbuvir to the patient with genotype 1b liver disease."

2. Generic Uses

- Example Sentence
- "Sofosbuvir is primarily indicated for the treatment of chronic hepatitis C virus (HCV) infection in adult patients without cirrhosis or with mild cirrhosis."

3. Antiviral Properties

- Example Sentence
- "The new medication developed, containing sofosbuvir, shows promising antiviral activity against the HCV infection."

4. Treatments in Combination

- Example Sentence
- "The effectiveness of sofosbuvir in combination with ribavirin in HCV infected patients, particularly in those with cirrhosis or severe liver disease, has been a focus of clinical trials."

5. Allocation of Drug Class

- Example Sentence
- "Sofosbuvir is a nucleotide inhibitor within the class of drugs referred to as direct-acting antivirals (DAAs)."

"Sofosbuvir" Similar Words

Sodomy

Sodomy refers to anal or oral intercourse between individuals of the same sex or between a person of the opposite sex and an animal. It is a sexual activity that is considered a crime in some jurisdictions and is widely considered to be taboo in many cultures. The term is derived from the biblical story of Sodom and Gomorrah, in which the cities are said to have been destroyed by God for the sins of their inhabitants, including sodomy.

Sods

A noun, the origin of which is derived from Old English 'sodd', which means a bundle of straw.

Soeharto

Suharto, also spelled Soeharto, is the pseudonym of Suharto (6 June 1921 – 27 January 2008), the second President of Indonesia, who served from 1967 to 1998.

Soekarno

Soekarno was the first President of Indonesia, serving from 1945 to 1967. He was a dominant figure in Indonesian politics and a key leader in the Indonesian National Revolution. Born on June 6, 1901, in Surabaya, Indonesia, Soekarno was a multi-talented individual who was a successful politician, orator, and statesman. Soekarno's real name was Sukarno and he was the son of a Javanese father and a Eurasian mother. His father, Kus Noer Ali, was a successful businessman who died when Sukarno was just a child. After his father's death, Sukarno was raised by his stepmother in the household of Raden Soekamano, a prominent teacher and lawyer. Sukarno went on to study law and engineering at the Technische Hoogeschool BPOOL (now the Bandung Institute of Technology) and later became involved in politics. He joined the Indonesian Nationalist Movement and quickly rose through the ranks, becoming one of the leaders of the movement. On August 17, 1945, Sukarno declared Indonesia's independence in front of a crowd of thousands in Jakarta, marking the beginning of the Indonesian National Revolution. He was appointed as the country's first President by the National Committee for Indonesian Independence, with Hatta as his vice president. During his presidency, Sukarno implemented a series of policies aimed at promoting nationalism and socialism. He built Kamboja-style temples, inspired by Khmer architecture, and built resorts in Indonesia. One of his most notable policies was to reform the feudal system in rural areas, which had once been ruled by Dutch colonizers. However, Sukarno's rule was marked by authoritarianism, including banning strikes and protests and narrowly allow political parties. Opposition to his rule grew, and an attempted coup in 1965, known as G30S, led to a military coup and the eventual downfall of Sukarno from power. Sukarno passed away on June 21, 1970, in Jakarta, at the age of 69.

Sofa

A sofa, also known as a couch or settee, is a piece of furniture designed for sitting or reclining, typically designed for multiple users and often with a back and arms.

Sofas

Long, upholstered pieces of furniture, typically with a back, arms, and cushions, designed for seating and relaxing, often found in living rooms or sitting rooms.

Sofer

A sofer (also spelled sopher or soffaer) is a Jewish scribe who is trained in the sacred craft of writing sacred Jewish texts by hand, such as the Torah. To be considered a sofer, one must undergo extensive training in calligraphy and be knowledgeable in Jewish law and tradition regarding the proper writing and formatting of these texts. Their work is considered a sacred trust, and their handwritten copies of the Torah are highly revered and often passed down through generations.

Sofia

Soft-boiled

Cooked in boiling water for 6-8 minutes, resulting in a runny yolk and a set white.

Soft-headed

Weak-minded or lacking in firmness of purpose or decision.

Soft-hearted

Soft-pedal

To soften or modify something in order to make it less severe or unpleasant, often in order to avoid causing offense or controversy. Example: The company downplayed the risk, soft-pedaling on the dangers of the new drug to keep investors happy.

Soft

Soft refers to something that is not firm or hard to the touch; having a gentle or yielding texture. Example: "The soft blanket was a comfort to snuggle up with." It can also describe something that is easy to deal with or requires minimal effort; not severe or harsh. Example: "The teacher gave us a soft hint to help us understand the concept." Additionally, soft can refer to a sound that is not loud or harsh; having a gentle or muted quality. Example: "The soft piano music created a soothing atmosphere." In a figurative sense, soft can describe someone or something that is gentle, kind, or yielding in nature. Example: "She has a soft spot for stray animals." It can also describe a policy or approach that is gentle and not strong or firm. Example: "The government implemented a soft approach to handle the economic crisis."

Softball

Softball is a bat-and-ball game similar to baseball. It is played by two teams, one playing offense (batting) and the other playing defense (fielding). In softball, a female pitcher throws the ball through a circular region of a large diamond-shaped infield. The objective is to strike or catch the thrown ball using a bat, scoring points by running around the four bases on the field.

Softboiled

Soft-boiled refers to something that is cooked lightly, especially eggs, in milk or water but not hard. The term is often used to describe a type of egg dish in which the yolks are still runny. It can also be used to describe a genre of mystery novels that are lighter and more humorous than traditional whodunits, often featuring an amateur detective who often solves the mystery before the official detective, with a simpler and more frivolous plot than typical detective fiction.

Soften

To make or become less sharp or severe; to become less firm or rigid; to reduce the severity or intensity of something. Example: "The chef added more milk to soften the sauce."