"Sialyltransferase" Pronounce,Meaning And Examples

"Sialyltransferase" Natural Recordings by Native Speakers

Sialyltransferase
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"Sialyltransferase" Meaning

Sialyltransferase is an enzyme that transfers sialic acid to the 2,3,6, or 9-hydroxyl groups of galactose or N-acetylglucosamine in the terminal position of glycoconjugates. It plays a crucial role in the biosynthesis of sialylated glycoconjugates, which are important in various biological processes, such as cellular recognition, signaling, and immune responses.

"Sialyltransferase" Examples

Sialyltransferase Usage Examples


Biological Context

GalNAc-4-sialyltransferase plays a crucial role in the regulation of the glycosylation pattern necessary for the function of transferrin.

Medical Context

The activity of saturated very-long-chain acyl-CoA dehydrogenase is mediated by 6,8-dithiooctanoyl-CoA and glycosyl-deficient sialyltransferase is inhibited by galactosemia.

Biochemical Context

Catalysis of the glycosyltransfer reaction in which CMP-Neu5Ac acts as the donor of the sialyl group.

Computational Context

Studies have been performed on the catalytic mechanism and the substrate specificity of Streptococcus pneumoniae sialyltransferase using quantum mechanical calculations.

Pharmaceutical Context

Mutants of Cel2A1, an exosome stimulated sialyltransferase of Caulophyllum thalictroides, have been engineered to have improved stability and thermal stability and glycosylation activity.

"Sialyltransferase" Similar Words

Sialometric

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Sialometry

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Sialoquent

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Loquacious, talkative, and verbose, but often to excess or irrelevantly so.

Sialorrhea

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Sialorrhea is a medical term that refers to excessive drooling or excessive saliva production. It can be a symptom of a variety of conditions, including neurological disorders such as Parkinson's disease, cerebral palsy, and brain injury, as well as other conditions like gastroesophageal reflux disease (GERD), as well as certain medications.

Sialorrhoea

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Sialylate

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Sialylated

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The word "sialylated" refers to a chemical modification of a molecule, specifically the addition of a sialic acid residue to another molecule, typically targeting the nitrogen atom of a terminal galactosyl (Gal) or N-acetylgalactosaminyl (GalNAc) residue. This process is an important post-translational modification in biology.<br><br>Sialylation is commonly found on the surface of cell membranes, where it plays a role in cellular recognition, adhesion, and interactions. It is essential for various biological processes, including cell signaling, immune responses, and neurotransmissions. In cancer cells, sialylation is often altered, leading to changes in cell-cell interactions and tumor progression.<br><br>Sialylated molecules can also be used as biomarkers for various diseases, such as cancer and viral infections. They can be detected using techniques like mass spectrometry and thin-layer chromatography.<br><br>In summary, sialylation is a significant post-translational modification that plays a crucial role in various biological processes and has potential applications in disease diagnosis and understanding cellular interactions.

Sialylation

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Siam

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Siamang

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Siamese

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Sian

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Sibelius

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Siberia

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Siberian

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Siberians

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Nouns:<br><br>1. People from Siberia, a region in Russia.<br>2. A breed of domesticated cat known for its thick fur and cold-climate adaptability.<br>3. A surname, possibly derived from the Russian name Sibir, meaning "of Siberia."<br><br>Vernacular:<br><br>1. People from Siberia may also refer to Inuit or other indigenous peoples living in Siberia.<br><br>Antonyms:<br>None explicit, but people living in more tropical climates would be antonyms.