"Quinazoline" Pronounce,Meaning And Examples

"Quinazoline" Natural Recordings by Native Speakers

Quinazoline
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"Quinazoline" Meaning

A heterocyclic compound, a six-membered ring containing five carbon atoms and one nitrogen atom.

"Quinazoline" Examples

Quinazoline Examples


1. Chemical Context

Quinazolines are a class of heterocyclic compounds that include fused benzene and pyrazine rings. They are structurally related to quinolines, but with a nitrogen atom substituted at the 2-position in place of carbon.

2. Pharmaceutical Importance

Quinazoline is a key framework in many drugs, including somatostatin receptor antagonists (SRTAs) and inhibitors of certain kinases. For example, sunitinib (sutent) targets a tyrosine kinase receptor and is used in the treatment of certain cancers.

3. Industrial Applications

One important aspect of quinazoline chemistry is their synthesis, which often involves complex multi-step sequences. The pharmaceutical interest in quinazolines stems from their potential as therapeutic drugs, which drives research into more efficient synthesis methods.

4. Natural Occurrence

Some natural products derived from fungi and plants contain quinazoline or quinolinone skeletons, which have displayed a range of biological activities, including antimalarial properties in specific cases.

5. Synthesis Pathways

The syntheses of quinazoline derivatives can vary widely, from direct procedures starting from readily available precursors through multi-step conversions involving additional transformations and coupling reactions. The choice of method can depend on the target molecule's complexity and the desired yield.

"Quinazoline" Similar Words

Quinacrine

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Quinacrine is a medication that was historically used to treat malaria and certain parasitic infections. It was also used as a treatment for symptoms of crabs or effluvium when applied topically, but it is now considered a treatment for aggressiveness associated with Koro and for urinary incontinence as well as attention deficit hyperactivity disorder.<br><br>In addition, Quinacrine has been studied as a potential treatment for Alzheimer's disease, depression, bipolar disorder, menopausal flashes, motion sickness, penile fibromas and retinal detachment.

Quinaldine

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Quinaldine is an organic compound with the formula (C6H5)2CHCHNH. It is a colourless liquid with a weak characteristic boiling point of 156-157 °C. It was first synthesised by the American chemist Joseph Moran in 1891 and after that by Edward Dean Adams in a similar year. Quinaldine is a parametidine (α,α',β,β'-tetramethyldelycidine), a metamizer.

Quinapril

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Quinapril is a medication used to treat high blood pressure and heart failure.

Quinaretic

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Quinary

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Quinary refers to the number 5 or something related to the number 5. It can also refer to a numeral system that uses 5 as its base.

Quinate

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Quinault

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Quinault is a word that can have several meanings, but primarily it refers to:<br><br>1. <strong>Quinault River</strong>: a river located in the Olympic Peninsula in the U.S. state of Washington.<br>2. <strong>Quinault Indian Tribe</strong>: a federally recognized tribe living in the Pacific Northwest, specifically in the Quinault Reservation in Grays Harbor County, Washington.<br>3. <strong>Mount Quinault</strong>: a prominent mountain in the Olympic Mountains.<br>4. <strong>Quinault (musical composition)</strong>: a musical composition for trombone and piano by Julien Tolbecq.<br><br>However, in linguistic terms, the term "Quinault" can also refer to the:<br><br>1. <strong>Quinault language</strong>: a Salishan language spoken by the Quinault people.<br>2. <strong>Quinault grammar and vocabulary</strong>: the study and analysis of the Quinault language and its linguistic features.<br><br>It is also possible that "Quinault" refers to other specific contexts, but these are the primary meanings associated with the term.

Quinazol

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Quinazoline is a type of heterocyclic aromatic organic compound that contains two adjacent nitrogen atoms in a single six-membered ring, fused to either a five-membered or a six-membered benzene ring. It is related to the benzoquinazoline class but the two benzene rings are in the 1,4 positions.

Quinazolinone

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Quinazolinones

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Quincampoix

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Quincampoix is a type of wild garlic that is native to France and other parts of Europe. It has broad, flat leaves and is often used in French cuisine in sauces, soups, and salads.

Quince

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Quinceanera

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A quinceañera is a celebration marking a girl's 15th birthday in many Latin American countries, typically Mexico, Chile, and Peru. The term translates to "fifteen years." The celebration is considered an important milestone in a young woman's life, symbolizing her transition from childhood to young womanhood. It often includes a grand party or ball, gifts, and a separation ceremony where the girl symbolically breaks up from her childish past. Family, friends, and community join to honor the celebration.

Quincentennial

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The word "quincentennial" refers to a 500th-anniversary celebration. It is often used to describe a period of commemoration that takes place every 500 years.

Quinces

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Quinces are a type of fruit that is often golden-yellow in color and has a soft, grainy texture. They are native to the eastern Mediterranean and have been cultivated for centuries for their unique flavor and alleged medicinal properties. Quinces can be eaten raw or cooked, and are often used to make jams, jellies, and perfumes.<br><br>The fruits of the quince tree (Cydonia oblonga) are characterized by their large size, usually around 5-10 cm in diameter, and their single, waxy bloom. They are often too tart to eat fresh, but are commonly used to make traditional dishes like quince paste, quince jelly, and quince cheese.<br><br>Quinces have a rich history, dating back to ancient Greece and Rome, where they were used in various rituals and ceremonies. Today, they are still valued for their culinary and medicinal uses, as well as their ornamental value in gardens and landscapes.

Quincewort

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Quincewort is a type of flowering plant, specifically a member of the daisy family (Asteraceae) known for its beautiful flowers and edible fruit.