"Pyrrolopyrazine" Pronounce,Meaning And Examples

"Pyrrolopyrazine" Meaning

A pyrrolopyrazine is a heterocyclic compound containing both a pyrrole and a pyrazine ring fused together. It is a type of aromatic compound, and its structure consists of a six-membered pyrazine ring fused to a five-membered pyrrole ring.

Pyrrolopyrazines are a type of bioactive compound that have been found to exhibit a range of biological activities, including antimicrobial, antifungal, and antitumor properties. They have also been used as intermediates in the synthesis of other compounds, such as pharmaceuticals and agrochemicals.

The name "pyrrolopyrazine" comes from the pyrrole and pyrazine components, which are derived from the words "pyrrole" (a five-membered ring containing one nitrogen atom) and "pyrazine" (a six-membered ring containing two nitrogen atoms).

"Pyrrolopyrazine" Examples

Pyrrolopyrazine Usage Examples

1. Chemical Context

Pyrrolopyrazine, a six-membered heterocyclic compound, forms the core of some pharmaceuticals and organic dyes:
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The team of chemists successfully synthesized a novel pyrrolopyrazine derivative with high fluorescence, which holds great promise for bioimaging and sensing applications.

2. Spectroscopy

In detail, the ultraviolet spectrum of the purified pyrrolopyrazine showed a strong absorption band at 220 nm, characteristic of the pyrazine ring.
python
from molecule import draw_molecule

moleculeimage drawmolecule('pyrrolopyrazine')

3. Pharmaceuticals

Researchers found that pyrrolopyrazine-based compounds have pharmacological activity, notably as potassium channel blockers and cancer treatment agents. These findings opened up new avenues for drug discovery.
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In the past few years, more than a dozen pyrrolopyrazine-based small molecules have entered clinical trials as treatments for cancer or heart disease.

4. Organic Synthesis

The synthesis of pyrrolopyrazine involves a four-step process from pyridine derivatives under controlled conditions: acid-catalyzed reaction, cyclization, dehydrogenation, and finally, substitutions to target compounds.
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High temperatures and pressures are required for the formation of the necessary pyrrolopyrazine structure from the given stabilizer.

5. Material Science

Pyrrolopyrazine derivatives can be attached to a polymer backbone to create materials with enhanced solubility and thermal stability, useful for organic electronics or optoelectronics applications.
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A wide range of pyrrolopyrazine-bearing polymers has been synthesized with significant improvements in the field of organic electronics, predicting highly efficient devices.