"Prothionamide" Pronounce,Meaning And Examples
"Prothionamide" Natural Recordings by Native Speakers
"Prothionamide" Meaning
Prothionamide is a prodrug of thionamide, which is an antituberculosis medication used to treat tuberculosis. It is a sulfur-containing compound that is converted to thionamide in the body, which then inhibits the synthesis of ATP in the pathogen, thereby inhibiting its growth and replication.
"Prothionamide" Examples
Usage Examples of "Prothionamide"
1. Medical Contexts: Prothionamide is used in the treatment of active tuberculosis. It has bacteriostatic and bactericidal effects on M. tuberculosis but is not used as a primary treatment currently. Combination therapy is effective due to its lack of potency against initial drug-resistant M. tuberculosis.
2. Academic Discussions: In a study, prothionamide efficacy against drug-resistant TB strains was compared with traditional treatments, highlighting its complementary role in managing drug-resistant cases.
3. Bacteriological Research: Researchers at the TB reference lab analyzed the use of prothionamide in multidrug-resistant TB cases showing potential drawbacks of reliance on prothionamide with its inherent drug-induced resistance.
4. Lecture on TB History: Class lectures reflect on past uses of thionamide drugs in treating tuberculosis (TB) in the 1950s-60s before progression issues were discovered. Prothionamide was part of these initial treatments.
5. Compound Analogs Synthesis: Recent development projects pushed the boundary of antimicrobial compound synthesis through formulation of new prothionamide analogs.
"Prothionamide" Similar Words
Protestor
Protests
Public demonstrations or displays of discontent, usually to express opposition to particular policies, decisions, or conditions. These can be peaceful or violent, and are often organized by groups of people who share a common concern or grievance.
Proteus
Prothalamia
Prothalamion
A Prothalamion is a poem written to celebrate a wedding or other joyous occasion. It is a type of occasional poem, typically formal and elaborate, that expresses congratulations and good wishes to the newlyweds. The term "Prothalamion" comes from the Greek words "pro" (before) and "thalamos" (bridal chamber), and was first used in the 16th century to describe a poem written before a wedding. The most famous Prothalamion is a poem by Edmund Spenser, written in 1591, which celebrates the wedding of Earl Henry Carey and Elizabeth Trego.
Prothallial
Prothesis
Prothetic
Prothonotary
An official or chief clerk, especially in the United States, who assists a judge and keeps the records of a court.
Prothoracic
Prothoracicotropic
Prothoracicotropic hormone (PTTH) refers to a peptide hormone produced by the brain of insects, particularly in the corpora cardaca of insects that undergo a complete metamorphosis. PTTH is released in response to a decrease in juvenile hormone levels, indicating that the larva has reached the end of its growth phase and is ready to transition to the pupal state, where it undergoes dramatic transformations en route to becoming the adult form.<br><br>PTTH acts on the prothoracic gland, stimulating it to produce ecdysone, a steroid hormone which initiates molting, a critical aspect of the process. In essence, PTTH is a hormone that effectively triggers the final stages of an insect's life cycle.
Prothorax
The prothorax is the middle segment of an insect's thorax, which is the section of the body behind the head and ahead of the abdomen. It bears most of the insect's legs and wings.
Prothoraxic
Prothrombinase