"Polymicrogyria" Pronounce,Meaning And Examples

"Polymicrogyria" Meaning

Polymicrogyria is a rare brain malformation characterized by an excessive number of small folds (gyri) on the brain's surface. This condition can affect various parts of the brain, including the cerebral cortex, cerebellum, or brainstem.The term "polymicrogyria" comes from the Greek words "poly" (many) and "microgyria" (small folds). In individuals with polymicrogyria, the normal six-layered structure of the neocortex is often disrupted, leading to a decreased distance between the gyri and an abnormal cortical lamination pattern.Polymicrogyria can be classified into different subtypes based on its location and extent, which can help clinicians diagnose the condition more accurately. Some common subtypes include:1. Perisylvian cortical polypmicrogyria: affects the sylvian fissure area.2. Bilateral perisylvian polymicrogyria: affects both sides of the sylvian fissure area.3. Landau-Kleffner syndrome (LKS): affects the language areas of the brain.4. Subcortical band heterotopia: involves abnormal band-like structures in the subcortical area.Symptoms of polymicrogyria vary greatly among affected individuals, depending on the extent and location of the brain malformation. People with polymicrogyria may experience developmental delays, seizures, intellectual disability, speech and language difficulties, and muscle weakness or paralysis.

"Polymicrogyria" Examples

5 Usage Examples

1. Medical Context Polymicrogyria is a rare and usually very serious form of cortical dysplasia, a congenital defect that involves the brain.##

2. Academic PaperPolymicrogyria is a brain abnormality where there are an excessive number of folds, or gyri, typically found in the brain's outer layer, or cerebral cortex.###

3. Health ArticleA Ford Foundation-funded researcher has identified specific microRNAs associated with periventricular nodular heterotopia (PNH) and polymicrogyria as well as other brain malformations in animal models, which may ultimately lead to treatments for HH and related disorders.#### 4. Medical ReportPatient under the age of three diagnosed with polymicrogyria and delivered prematurely, which significantly affects brain development and shows possibility of respiratory infection.#### 5. Clinical PresentationThe congenital form of focal cortical dysplasia is the most common cause of seizures, and can include polymicrogyria, an abnormal brain folding disorder that can vary across the brain's regions and may be symmetrical or asymmetrical.