"Parakeratotic" Pronounce,Meaning And Examples

"Parakeratotic" Meaning

Parakeratotic refers to a type of cell in the skin, particularly in the epidermis, that remains in its immature state and retains its nucleus. This typically occurs in response to chronic inflammation or irritation, and is often seen in conditions such as psoriasis. In a normal skin environment, the cells would typically undergo a process called keratinization, where they lose their nuclei and differentiate into the hardened, dead cells that make up the outer layer of the skin. In parakeratotic cells, this process is disrupted, and the cells instead retain their nuclei and remain in a state of hyperplasia.

"Parakeratotic" Examples

Usage Examples for "Parakeratotic"

In a dermatopathology report, the pathologist noted that the skin lesion was characterized by parakeratotic cells, which indicated a certain type of keratinocyte cell death.
The study on the histopathology of skin cancers showed that the parakeratotic layer in the epidermis was not as thick as expected, which suggested an early stage of cancer development.
During the autopsy, the forensic pathologist observed parakeratotic changes in the skin tissue, which helped to establish the cause of death as exposure to high temperatures.
In the histology textbook, it was explained that parakeratotic cells are formed when keratinocytes retain their nucleus and other organelles during the process of differentiation, leading to a characteristic finding in skin pathology.
The patient's skin biopsy revealed parakeratotic changes in the stratum corneum, which was consistent with the diagnosis of a skin condition.