"Myristoylated" Pronounce,Meaning And Examples

"Myristoylated" Meaning

Myristoylated refers to a protein or peptide that has been covalently modified by the addition of a myristate (a 14-carbon saturated fatty acid) group to its amino acid sequence. This modification typically occurs at the N-terminal cysteine residue and allows the protein to bind to membranes and behave as a peripheral membrane protein. Myristoylation is often encountered in signal transduction and protein kinase proteins. It helps to target these proteins to specific cellular locations and regulate their activity.

"Myristoylated" Examples

Here are 5 usage examples based on the word "myristoylated":

In scientific research

The researchers used myristoylated peptides to study the binding properties of protein receptors.
The myristoylated protein was found to be essential for the proper functioning of the cell signal pathway.

In biochemistry

The myristoylated amino acid sequence was identified as a key feature of the protein structure.
The myristoylated targeting sequence was used to direct the protein to the correct intracellular compartment.

In molecular biology

The myristoylated protein was found to be localized to the plasma membrane, where it played a key role in cell signaling.
The myristoylated fusion protein was used to study the transport of proteins across cell membranes.

In biomedical engineering

The researchers designed a myristoylated nanoparticle to target and deliver therapeutic agents to specific cells.
The myristoylated protein was used as a scaffold for tissue engineering applications.

In protein science

The myristoylated protein was found to have altered substrate specificity after being treated with a specific enzyme.
The myristoylated protein was used to study the role of lipid modification in protein function and trafficking.