"Metabotropic" Pronounce,Meaning And Examples

"Metabotropic" Natural Recordings by Native Speakers

Metabotropic

"Metabotropic" Meaning

Metabotropic refers to receptors on the surface of cells that respond to neurotransmitters by triggering a complex series of chemical reactions within the cell, often with slower and more sustained effects than ionotropic receptors.

"Metabotropic" Examples

Usage Examples for "Metabotropic"

Biology

Metabotropic receptors are a type of receptor protein found in the plasma membrane of certain cells, which respond to diffusible ligands by triggering changes in the activity of second messenger systems.

The metabotropic receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of certain neurological disorders.
The binding of a neurotransmitter to a metabotropic receptor triggers a cascade of downstream signaling events.

Pharmacology

Metabotropic agonists are a class of drugs that activate metabotropic receptors, which can produce a range of physiological effects.

Baceylofen, a metabotropic agonist, is used to treat anxiety disorders by modulating the activity of GABA receptors.
The metabotropic antagonist LY367385 has been shown to have anti-anxiety properties.

Neuroscience

Metabotropic receptors play a crucial role in many neural processes, including learning and memory, synaptic plasticity, and the regulation of mood.

The metabotropic receptor mGluR1 is involved in the regulation of excitatory synaptic transmission in the hippocampus.
The activation of metabotropic receptors in the hippocampus is thought to be involved in the formation of long-term memories.

Molecular Biology

Metabotropic receptors are known for their allosteric mechanism of action, which involves the binding of a ligand to a distinct site and subsequently affecting the activity of a separate binding site.

The crystal structure of the metabotropic receptor mGluR1 has provided valuable insights into the molecular mechanisms of receptor activation.
The binding of a metabotropic antagonist to the receptor can shift the equilibrium between the active and inactive conformations.

Clinical Research

Metabotropic receptors have been implicated in various diseases, including various neurological and psychiatric disorders.

Research has shown that alterations in metabotropic receptor expression and function may contribute to the development of depression.
The study of metabotropic receptors in disease states has led to the development of new therapeutic strategies.

"Metabotropic" Similar Words

Metabolized

Metabolized refers to the process by which the body converts food into energy. It involves a series of chemical reactions that break down the nutrients in food into a form that the body can utilize. For example, carbohydrates are metabolized into glucose, which can be used by the body for energy or stored in the liver and muscles for later use.

Metabolizer

A metabolizer is a substance or enzyme that facilitates the metabolism of a larger molecule, breaking it down into smaller components or converting it into a more usable form for the body. It plays a crucial role in many biological processes, such as the breakdown of nutrients, the elimination of toxins, and the regulation of hormone levels.

Metabolizes

Metabolizes is a verb that means to break down and convert (a substance) into simpler compounds, especially in the body: a process by which the body converts food into energy.

Metabolizing

Metabolome

The metabolome is the collection of all the metabolites, or small molecules, found within an organism. It is often referred to as the "molecular phenotype" of an organism, as it represents the end product of various biochemical reactions and pathways within the cell. The metabolome is distinct from the genome, which refers to the genetic sequence of an organism, and the transcriptome, which refers to the collection of RNA transcripts from those genes. Understanding the metabolome is important for understanding an organism's physiology, disease state, and response to environmental or pharmacological stimuli.

Metabolomic

Metabolomics

Metabolous

Metabolous refers to the metabolism, which is the process by which living organisms convert food into energy and maintain life.

Metabranchial

Metacarpal

Metacarpals

Metacarpectomy

Metacarpi

The term "metacarpi" refers to the five long bones of the hand that connect the wrist to the fingers.

Metacarpophalangeal

Metacarpus

The metacarpus is the intermediate bone structure of the hand, connecting the wrist bones to the phalanges (fingers). It consists of five bones (first to fifth metacarpal bones) that house the tendons and ligaments that allow for finger movement. The metacarpus is also sometimes referred to as the "hand" or "forearm", although the term "hand" typically includes the wrist and fingers as well.