"Isostere" Pronounce,Meaning And Examples
"Isostere" Natural Recordings by Native Speakers
"Isostere" Meaning
An isostere is a molecule that has the same three-dimensional shape as another molecule, but has a different chemical structure. In other words, isosteres are molecules that have the same spatial arrangement of atoms as each other, but have different chemical properties.
"Isostere" Examples
Isostere
A chemical structure that is isosteric with another compound means it has the same shape and bonding arrangements, but potentially different substituents.
Examples:
The compounds in Figure 1 are isosteres because they have the same skeletal structure, but have different substituents at the R1 and R2 positions.
In medicinal chemistry, designing isosteric analogs of biologically active molecules can help identify the key pharmacophore responsible for the desired activity.
By generating a series of isosteres, researchers can systematically evaluate the structural requirements for binding a particular enzyme or receptor.
The isostere principle has been widely applied in the design of new therapeutic agents, including drugs and agrochemicals.
In a study, researchers synthesized a series of isosteres to determine the optimal structure for a new antitumor agent.
"Isostere" Similar Words
Isosporic
Isosporic refers to the development or growth of an organism, such as a parasite, in which the different stages or forms of the organism, as they mature, are similar in size and shape, being identical or essentially indistinguishable from one another.
Isosporous
Isostacy
Isostacy is a geological term that refers to the condition of the Earth's lithosphere (outer layer of the planet) where the density of the crust is equal at all depths. In other words, isostacy occurs when the weight of the overlying crust is balanced by the buoyancy of the underlying mantle, resulting in a stable and uniform density distribution. This concept is important in plate tectonics and the formation of mountains and oceanic ridges.
Isostasy
Isostatic
Isostatic refers to an equilibrium state in which the weight of an object or a system is evenly distributed, causing it to be suspended or floating in mid-air due to the equal pressure from all sides, often seen in geology where the weight of rock is balanced by the pressure from the surrounding material, resulting in a stable and stable condition.
Isostearamide
Isostemonous
Isostemonous is an adjective that refers to the arrangement of leaves on a stem. In botany, it describes a type of phyllotaxis, where leaves are arranged in a spiral pattern on the stem, with each leaf replaced by one at a right angle to the previous one. This pattern is often seen in plants such as bamboo, papyrus, and palm trees.
Isostemony
Isostemony refers to a condition in which the sepals (petal-like leaves that protect and support flowers) are more or less equal in size and shape to the petals in a flower. It is a characteristic often found in certain types of flowers, particularly those in the orchid and lily families.
Isosteres
Isosteres refer to molecules or ions that have similar chemical properties due to the same number and arrangement of electrons in their outermost energy level, despite having different atomic numbers and positions in the periodic table. In other words, isosteres are molecules that have the same shape and size, but differ in their atomic composition.
Isosteric
Isosteric refers to the condition where two or more substances have the same temperature and pressure but different compositions.
Isosterism
Isosthenuria
Isosthenuria is a medical condition characterized by a urine concentration that is near the normal level of the kidney's maximum ability to concentrate urine, namely 1.030-1.040 grams per milliliter. This is a normal or near-normal urine specific gravity.
Isosthenuric
Isostructural
Isosulphocyanate
Isosulphocyanic
Isonitrosulphocyanic is a chemical compound that is a mixture of nitrates and cyanides. It is often used in the synthesis of otherchemical compounds and inorganic substances.