"Farnesylation" Pronounce,Meaning And Examples

"Farnesylation" Meaning

Farnesylation is a type of lipid modification that is involved in the post-translational modification of proteins. It refers to the addition of a farnesyl group, a hydrophobic fatty acid chain, to the C-terminal cysteine residue of a protein. This modification is important for the proper functioning of many proteins, particularly those involved in signal transduction pathways.

"Farnesylation" Examples

Farnesylation

Meaning

Farnesylation is a post-translational modification in which a farnesyl group is attached to a protein.

Usage Examples

1. Research Paper

In this study, we investigated the role of farnesylation in the regulation of protein stability and trafficking in the cell.

2. Scientific Article

Farnesylation of certain proteins is essential for their translocation to the plasma membrane, where they can participate in signaling pathways.

3. Scientific Presentation

Farnesylation is a common modification found in many proteins, including ras proteins, which are involved in cell proliferation and differentiation.

4. Academic Journal

The farnesylation of proteins can be inhibited by specific enzymes, leading to a decrease in their activity and altered cellular function.

5. Technical Report

Farnesylation is a crucial step in the biogenesis of certain proteins, and any defects in this process can lead to protein misfolding and aggregation.