"Excitotoxic" Pronounce,Meaning And Examples

"Excitotoxic" Meaning

Excitotoxic refers to a type of reaction in which a neurotransmitter, often glutamate, binds to its receptor in the brain, leading to an over-stimulation and ultimately, the death of the affected brain cells.

"Excitotoxic" Examples

Examples of "Excitotoxic"

1. Medical Context

Glutamate, a type of neurotransmitter, can be excitotoxic to brain cells if released in excessive amounts, leading to neurodegenerative conditions like Alzheimer's disease and Parkinson's disease.

2. Scientific Research

The researcher studied the effects of excitotoxicity in the brain after a traumatic injury and found that it contributed to the development of chronic traumatic encephalopathy (CTE).

3. Neurology

The neurologist diagnosed the patient with excitotoxicity-induced neurodegeneration, resulting from a severe head injury sustained during a car accident.

4. Cell Biology

In cell culture experiments, scientists observed that excessive stimulation of glutamate receptors led to excitotoxic cell death in hippocampal neurons.

5. Pharmacology

The new medication aimed to reduce excitotoxic damage in the brain by blocking the action of glutamate, a key player in neurodegenerative diseases.

Note: Excitotoxic refers to the death of neurons or other cells caused by excessive activation of receptors that normally respond to excitatory neurotransmitters like glutamate.