"Citrullination" Pronounce,Meaning And Examples

"Citrullination" Meaning

Citrullination is a post-translational modification of proteins in which an amino acid called citrulline is inserted into the protein in place of the amino acid arginine. This process is often referred to as a "deimination" reaction. Citrullination is a key step in the formation of citrullinated proteins, which have been implicated in various physiological and pathological processes, including autoimmune diseases such as rheumatoid arthritis and cancer.

"Citrullination" Examples

Citrullination

Citrullination is a biochemical process in which the amino acid citrulline is incorporated into a protein. Here are 5 usage examples:

Biological context: Citrullination is a key post-translational modification in the regulation of protein function, involved in the development of arthritis and other autoimmune diseases.
Research article: "The citrullination of histone H4 is a critical step in the regulation of DNA repair pathways in response to oxidative stress."
Medical journal: "Citrullination of collagen is a hallmark of several autoimmune diseases, including rheumatoid arthritis and lupus erythematosus."
Scientific conference: "We investigated the role of citrullination in the regulation of protein-protein interactions in cancer cells."
Academic paper: "Citrullination is a novel target for the development of therapeutic interventions for autoimmune diseases, offering a promising approach to prevent tissue damage and promote tissue repair."