"benzylic" Pronounce,Meaning And Examples
"benzylic" Natural Recordings by Native Speakers
"benzylic" Meaning
"Benzylic" refers to a carbon atom in an organic compound that is directly attached to a benzene ring. This carbon is part of the aromatic system and can participate in various chemical reactions due to its location and electron-rich nature associated with the benzene ring.
"benzylic" Examples
The word "benzylic" refers to a carbon atom in an organic compound that is directly attached to a benzene ring. Here are five usage examples:
1. Chemical Reactivity: Benzylic positions are known to be more reactive than alkyl groups due to the electron-donating nature of the aromatic ring, which can stabilize positive charge intermediates.
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The benzylic carbon in the compound undergoes electrophilic substitution reactions more readily than its non-benzylic counterparts.
2. Synthetic Chemistry: In organic synthesis, benzylic positions are often targeted for functional group introduction or manipulation because they offer a handle for further transformations.
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During the synthesis of a pharmaceutical compound, a protecting group was installed at the benzylic position to prevent unwanted side reactions.
3. Catalytic Hydrogenation: Benzylic compounds can be selectively hydrogenated over certain catalysts, with the hydrogen preferentially adding to the benzylic carbon.
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In the presence of palladium on carbon catalyst, the benzylic double bond in the molecule was efficiently hydrogenated to afford the saturated product.
4. Stereochemistry: Benzylic stereocenters can have significant implications in the biological activity of a compound, as their configuration can influence how the molecule interacts with its target.
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The enantiomers of a benzylic amino acid derivative exhibited different pharmacological profiles due to their distinct spatial arrangements around the chiral center.
5. Analytical Chemistry: Chromatographic techniques can separate benzylic compounds from other structural isomers based on their unique interaction with stationary phases.
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In gas chromatography, benzylic alcohols were effectively separated from primary and secondary alcohols due to their distinct retention times on a polar column.
"benzylic" Similar Words
Benzothiazepine
Benzothiazepine is a chemical compound belonging to the class of drugs known as benzodiazepines, which are used primarily as tranquilizers, sedatives, and anxiolytics. The "thiazepine" part of the name refers to the presence of a thiazole ring fused to a seven-membered diazepine ring. These medications work by enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, leading to a calming effect on the nervous system. Some specific benzothiazepines include clonazepam and diazepam.
Benzothiazepines
Benzothiazepines are a class of chemical compounds that combine the structures of benzene and thiazepine rings. They are primarily known for their pharmacological properties, particularly as tranquilizers or anticonvulsant drugs. These compounds can have various effects on the central nervous system, such as anxiolytic (anxiety-reducing), sedative, and muscle relaxant effects. Some benzothiazepines are used medicinally to treat anxiety disorders, seizures, and sleep disturbances, although they are less commonly prescribed than other medications like benzodiazepines due to concerns about tolerance, dependence, and withdrawal.
Benzothiazole
Benzothiazole is a chemical compound consisting of a benzene ring fused to a thiazole ring. It is an aromatic heterocycle, containing both nitrogen and sulfur atoms within its structure. Benzothiazole has various industrial applications, particularly as a component in fungicides, antioxidants, and corrosion inhibitors. It is also used in the synthesis of dyes, pharmaceuticals, and rubber chemicals.
Benzoyl
Benzoyl refers to a chemical compound containing a benzoyl group, which consists of a benzene ring attached to a carbonyl group (C=O). It is commonly used in organic chemistry and can be found in various substances, such as perfumes, dyes, and pharmaceuticals. Benzoyl peroxide, for example, is a well-known acne treatment.
Benzoylecgonine
Benzoylecgonine is a chemical compound that serves as a major metabolite of cocaine. It is formed when cocaine is processed in the body, particularly in the liver. Benzoylecgonine can be detected in urine for a longer period than cocaine itself, which is why it is commonly used in drug testing to determine recent cocaine use.
Benzydamine
Benzydamine is a nonsteroidal anti-inflammatory drug (NSAID) used as a local anesthetic and analgesic for oral and throat irritations. It is often found in mouthwashes, lozenges, or sprays to relieve pain and inflammation associated with sore throat, dental procedures, or minor mouth injuries. It works by reducing swelling and providing a numbing effect to alleviate discomfort.
Benzyl
Benzyl refers to a chemical compound or group derived from benzene, a aromatic hydrocarbon. It is represented by the formula C6H5CH2- and is commonly used in organic synthesis, perfumes, and pharmaceuticals. It can also be used as a prefix in naming compounds, indicating the presence of a benzyl group attached to another molecule.
Benzylamine
Benzylamine is an organic compound with the chemical formula C6H5CH2NH2. It is a colorless liquid with a characteristic amine odor. It is derived from benzyl alcohol and ammonia, and it is used as a precursor in the synthesis of various pharmaceuticals, dyes, and other chemicals. Benzylamine can act as a base and form salts with acids, and it also undergoes reactions typical of amines, such as nucleophilic substitution and addition reactions.
Benzylidene
Benzylisoquinoline
Benzylisoquinolinium
Benzylpiperazine
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Beoseon
Beothuk
Beotia