"bedaquiline" Pronounce,Meaning And Examples
"bedaquiline" Natural Recordings by Native Speakers
"bedaquiline" Meaning
Bedaquiline is an antituberculosis medication used to treat multidrug-resistant tuberculosis (MDR-TB). It is a diarylquinoline that works by inhibiting the ATP synthase enzyme of Mycobacterium tuberculosis, thereby disrupting the bacterium's energy production and leading to its death. It is usually prescribed as part of a combination therapy for MDR-TB cases, as mono-therapy can contribute to the development of resistance. Bedaquiline was approved by the US Food and Drug Administration (FDA) in 2012 and is under the brand name Sirturo.
"bedaquiline" Examples
Bedaquiline is an antitubercular medication used to treat multidrug-resistant tuberculosis (MDR-TB). Here are five usage examples:
1. Prescription Context: Dr. Thompson prescribed bedaquiline for John, who had developed resistance to standard TB drugs, as part of his comprehensive treatment plan.
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Dr. Thompson: "John, due to your MDR-TB, we'll be starting you on bedaquiline along with other medications to combat the resistant bacteria."
2. Clinical Trial: In a recent study, bedaquiline showed promising results in improving treatment success rates among patients with multidrug-resistant tuberculosis.
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Study Report: "The use of bedaquiline in the clinical trial led to a significant improvement in patient outcomes, reducing the failure rate and increasing cure rates."
3. Adverse Effects: Patients taking bedaquiline may experience QT interval prolongation, a potential cardiac side effect, necessitating regular monitoring.
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Patient Information Leaflet: "While on bedaquiline, it's important to inform your doctor if you feel any chest discomfort, as it could indicate a change in heart rhythm."
4. Access and Availability: Efforts are being made to increase access to bedaquiline in low-income countries where MDR-TB is more prevalent.
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Global Health News: "International organizations are working together to ensure that bedaquiline reaches those in need, particularly in resource-limited settings affected by MDR-TB."
5. Combination Therapy: Bedaquiline is typically used in combination with other drugs to enhance effectiveness and delay the development of further resistance.
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Medical Journal: "Bedaquiline, when combined with appropriate companion drugs, has demonstrated improved efficacy in treating MDR-TB, helping to combat the growing concern of antibiotic resistance."
"bedaquiline" Similar Words
Bed-roll
A bed-roll refers to a compact and portable sleeping arrangement, typically consisting of a mattress, blanket, and sometimes a pillow, rolled up together for ease of transport and storage. It is often used for camping or situations where a temporary sleeping space is needed.
Bed-sits
"Bed-sits" is a term used primarily in the United Kingdom and Ireland to describe a type of small, self-contained living space. It is a combination of a bedroom and a sitting room, typically found in apartments or houses that have been divided into individual units. A bed-sit usually consists of one room that serves as both a bedroom (with a bed) and a living area (with a sofa or seating), often with a separate kitchenette and bathroom shared with other residents. It is a more affordable housing option for individuals who require a private space but cannot afford a full one-bedroom apartment.
Bed-sitter
A "bed-sitter" is a room that combines the functions of a bedroom and a sitting room, typically found in apartments or hotels. It is a single space where one can sleep, relax, and entertain guests, as opposed to having separate bedrooms and living rooms.
Bed-time
Bed-time refers to the time when one goes to bed to sleep, typically at the end of the day. It is often associated with a routine, especially for children, involving activities such as brushing teeth, changing into pajamas, and reading a bedtime story before settling down for the night.
Bed-wetter
A "bed-wetter" is a person, especially a child, who involuntarily urinates during sleep. It is often used as a term to describe someone who has not yet overcome the challenge of staying dry at night or may be a reference to a person experiencing stress or anxiety-related incontinence. In some cases, it can be a medical condition, and in others, a phase that children eventually outgrow.
Bed-wetters
"Bed-wetters" is a term used to describe individuals, typically children, who involuntarily wet their beds during sleep. It can also be used metaphorically to refer to people who are perceived as being emotionally weak or prone to showing fear or anxiety in challenging situations.
Bed-wetting
"Bed-wetting" refers to the act of urinating involuntarily while sleeping, especially by children who have not yet gained full bladder control or by adults with medical conditions that affect bladder function. It is also known as enuresis.
Bed
"Bed" refers to a piece of furniture designed for sleeping, typically consisting of a frame with a mattress and often covered with a blanket or sheets. It can also be used metaphorically to express a situation or state, such as "in bed with" (to be closely associated with someone or something) or "hit the bed" (to go to sleep).
Bedarkened
Bedashed
Bedaub
Bedaubed
Bedaubing
Bedazzle
Bedazzled
Bedazzlement