"avelumab" Natural Recordings by Native Speakers
Avelumab is a medication that belongs to a class of drugs called monoclonal antibodies. It is used primarily in cancer treatment, specifically in immunotherapy. Avelumab works by targeting and binding to a protein called PD-L1 (programmed death-ligand 1) which is present on some cancer cells and immune cells. By blocking PD-L1, avelumab helps the immune system recognize and attack cancer cells more effectively. It is approved for the treatment of various types of cancer, including metastatic Merkel cell carcinoma and advanced bladder cancer.
Avelumab is a monoclonal antibody used in cancer immunotherapy. Here are five usage examples:
1. In metastatic Merkel cell carcinoma: Avelumab is approved for the treatment of adults and pediatric patients with metastatic Merkel cell carcinoma, a rare and aggressive form of skin cancer.
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- Avelumab has shown significant efficacy in managing metastatic Merkel cell carcinoma, providing hope for patients who have limited treatment options.
2. Combination therapy in advanced bladder cancer: Avelumab is sometimes used in combination with chemotherapy for treating advanced urothelial carcinoma, a type of bladder cancer.
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- In certain cases, doctors may prescribe avelumab along with platinum-based chemotherapy to improve survival rates in patients with advanced bladder cancer.
3. Immune-related adverse events: Like other immunotherapies, avelumab can cause immune-related adverse events, which require careful monitoring and management.
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- Patients receiving avelumab may experience immune-related side effects such as colitis or pneumonitis, necessitating prompt medical intervention.
4. Maintenance therapy: After initial treatment, avelumab can be administered as maintenance therapy to prevent disease progression in suitable patients.
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- Following first-line chemotherapy, some oncologists recommend avelumab maintenance therapy to prolong progression-free survival in patients with specific types of cancer.
5. FDA approval and clinical trials: Avelumab's approval by the US Food and Drug Administration (FDA) was based on positive results from several clinical trials.
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- The FDA approved avelumab based on the encouraging data from Phase III clinical trials demonstrating improved outcomes in patients with certain cancers compared to standard treatments.
"Avatar" refers to a representation or embodiment of a person, deity, or concept. In modern usage, it often denotes a custom-made digital character that a user creates to represent themselves in a virtual world, game, or online platform. The term also has historical roots in Hinduism and Buddhism, where it signifies the descent of a deity, especially Vishnu, into a human or animal form to intervene in the world.
Avatars refer to visual representations of users, often used in digital environments such as social media platforms, forums, gaming platforms, or virtual worlds. These images can be custom-made, pre-selected from a gallery, or in the form of icons, and they serve to identify and personalize a user's online presence. Avatars can be realistic portraits, cartoon characters, symbolic objects, or any other design that the user chooses to represent themselves.
The word "avaunce" is an archaic term that means to advance, promote, or raise to a higher position or level. It can also refer to an increase in value or status. In a historical context, it might be used when talking about elevating someone's social standing or advancing in a particular field. However, this word is not commonly used in modern English.
"Avaunt" is an archaic verb that means "to go away, depart, or be gone." It was often used as a command to dismiss or reject someone or something. In a broader sense, it can convey the idea of moving forward or advancing, but its usage today primarily leans towards the notion of getting rid of or sending away.
The word "avauntour" is not commonly used in standard English. It seems to be a combination of "avant" and "tour," which individually mean "before" or "in front of" (from French) and "journey" or "travel" respectively. However, "avauntour" is not a recognized term with a specific meaning in the English language. If you intended to refer to "aventure," it means "adventure."
"ave" is an abbreviation of "average," which refers to a value that represents the central tendency of a set of numbers. It is calculated by summing up all the numbers and dividing by the count of numbers. For example, if you have the numbers 2, 4, and 6, their average would be (2 + 4 + 6) / 3 = 4.
The word "aveline" is not widely recognized or has a specific meaning in mainstream English. It could potentially be a misspelling, a rare name, or a term that is not commonly used. If you meant "avocet," it refers to a type of wading bird with a long, upturned bill, typically found near coastal waters.
The word "avellane" appears to be a misspelled or unfamiliar term. It is possible that you meant "avellana," which refers to the hazelnut tree or its nuts. Hazelnuts are commonly used in cooking and baking and are known for their sweet, nutty flavor. If "avellane" was intended as a proper name or has a specific context, it would be helpful to have more information for a precise explanation.