"Atropisomer" Pronounce,Meaning And Examples
"Atropisomer" Natural Recordings by Native Speakers
"Atropisomer" Meaning
Atropisomer refers to a type of stereoisomer that arises due to restricted rotation around a bond, typically a single bond, in a molecule with an asymmetric arrangement of substituents. This restriction leads to two or more distinct spatial arrangements that cannot be interconverted by simple rotation. The term is derived from "atropos," one of the three Fates in Greek mythology who controlled the thread of life, symbolizing the inability to change the orientation of the substituents. Atropisomers often exhibit different chemical and physical properties because of their distinct conformations.
"Atropisomer" Examples
Atropisomer refers to a type of stereoisomer that arises due to restricted rotation around a bond, typically a single bond, in a molecule. The atropisomers have different spatial arrangements and can exhibit distinct properties. Here are five usage examples:
1. Drug Design: Atropisomers can be significant in pharmaceuticals, as their different conformations might lead to varying biological activities. For example, the drug Rofecoxib (Vioxx) had two atropisomers, one of which was responsible for its anti-inflammatory effects while the other contributed to increased cardiovascular risks.
2. Chiral Molecules: Some chiral molecules, like binaphthyl derivatives, can exist as atropisomers because of the limited rotation between the two aromatic rings. These compounds are used in asymmetric synthesis and as catalysts in organic chemistry.
3. Fluorescence Properties: The atropisomers of a molecule may display different fluorescence characteristics. For instance, a molecule with a fluorophore attached to a rigid scaffold can exhibit distinct emission spectra depending on the atropisomeric form.
4. Sensors: In molecular sensing, atropisomers can be exploited to design switches or indicators. A change in environment or binding event might cause a shift between atropisomers, leading to a detectable signal change.
5. Photochemistry: The photoisomerization of atropisomers is an area of interest in photochemistry. Upon absorption of light, a molecule can undergo a transition between atropisomers, which can be useful in developing light-responsive materials or molecular machines.
"Atropisomer" Similar Words
Atropinisation
Atropinisation refers to the process of administering atropine, a medication derived from the plant belladonna, to a person in order to produce a specific set of effects. This typically involves the use of atropine to block muscarinic acetylcholine receptors, which are involved in various autonomic nervous system functions. Atropinisation can result in a range of physiological responses, such as dilated pupils, dry mouth, increased heart rate, and decreased secretions. It is often used therapeutically to treat certain medical conditions or as an antidote for certain types of poisoning, particularly those involving excessive acetylcholine release.
Atropinise
The word "atropinise" is a verb that means to treat or medicate with atropine, a drug derived from plants like belladonna. Atropine is used to block certain types of nerve impulses, particularly in the muscarinic acetylcholine receptors, and is often employed in medical contexts to dilate pupils, dry secretions, or slow down the heart rate, among other effects.
Atropinised
"atropinised" is a term that refers to a condition where a person or an animal has been treated with atropine, a medication used to block the effects of certain nerve agents and to dilate the pupils in the eyes. It can also be used to refer to the state of being under the influence of atropine, which can cause a range of effects such as dry mouth, increased heart rate, and blurred vision. Atropine is an anticholinergic drug, and its use can counteract excessive activity of the parasympathetic nervous system.
Atropinization
Atropinization refers to the state or condition of having achieved a therapeutic level of atropine in the body. Atropine is a medication used to block the effects of certain neurotransmitters, particularly acetylcholine, and is often used in medical treatments, such as treating poisoning by nerve agents or managing certain heart conditions. Atropinization indicates that the patient has received enough atropine to produce the desired clinical effects, such as dilating the pupils, increasing heart rate, and drying secretions. However, it also implies that the patient may be at risk for side effects associated with atropine overdose if the dosage is not carefully monitored.
Atropinize
To "atropinize" means to administer or treat with atropine, a medication derived from certain plants, particularly belladonna. Atropine is used to block the effects of acetylcholine, a neurotransmitter, and has various medical applications such as dilating pupils, reducing secretions, and treating certain types of poisoning. The term "atropinize" refers to the process of inducing these effects in a patient through the use of atropine.
Atropinized
"atropinized" refers to a state or condition where a person or animal has been treated with or affected by atropine, a medication used to block the effects of certain nerve agents and to dilate the pupils in the eyes. It can also imply that the individual is experiencing the side effects or characteristics associated with atropine, such as dry mouth, increased heart rate, and blurred near vision.
Atropism
Atropism refers to the lack of orientation or response to a stimulus in a normal direction, typically observed in plants. It is the absence or deviation from the typical growth direction in response to external factors such as light, gravity, or touch. In other words, it is when a plant does not grow or bend towards or away from a stimulus as expected.
Atropisms
Atropisms refer to linguistic errors or peculiarities, particularly in the use of words, where there is a deviation from the standard or correct form. It usually involves incorrect word order, misuse of grammar, or malapropisms. These can be unintentional, as in the case of speech errors made by non-native speakers or individuals learning a language, or intentional, for comedic or rhetorical effect.
Atropisomeric
Atropisomers
Atropos
Atropous
Atrous
Atrovent
Atrypa
Atsm