"Antifolates" Pronounce,Meaning And Examples
"Antifolates" Natural Recordings by Native Speakers
"Antifolates" Meaning
Antifolates are a class of drugs that inhibit the action of folates, which are B vitamins (folic acid) essential for cell growth and reproduction. These drugs interfere with the metabolic processes that depend on folates, particularly those involved in DNA synthesis. They are often used as antineoplastic agents in cancer treatment to block the rapid division of cancer cells or as antimicrobial agents against parasites and some types of bacteria. Examples of antifolate drugs include methotrexate and trimethoprim.
"Antifolates" Examples
1. Antifolates are a class of drugs used to treat certain types of cancer, as they interfere with the metabolism of folate, hindering cell division and growth.
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- Example sentence: Chemotherapy regimens sometimes include antifolate medications to suppress rapidly multiplying cancer cells.
2. Methotrexate is an antifolate commonly prescribed for autoimmune diseases like rheumatoid arthritis, as it helps reduce inflammation by blocking the action of folic acid in the body.
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- Example sentence: Patients with rheumatoid arthritis may take methotrexate, an antifolate drug, to manage their symptoms.
3. Antifolates can have side effects such as mouth sores and gastrointestinal disturbances due to their impact on healthy cells that rapidly divide, like those in the digestive tract.
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- Example sentence: When undergoing treatment with antifolates, patients should be aware of potential side effects like nausea and mouth ulcers.
4. Prenatal vitamins often contain high levels of folic acid to counteract the effects of antifolates and prevent neural tube defects in developing fetuses.
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- Example sentence: Women planning to conceive are advised to take prenatal supplements rich in folic acid, which can help protect against the risks posed by antifolate medications.
5. Some parasites, like malaria-causing Plasmodium species, have developed resistance to antifolate drugs, necessitating the development of new combination therapies.
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- Example sentence: To combat drug-resistant malaria, researchers are exploring antifolate combinations with other antimalarial drugs to enhance treatment efficacy.
"Antifolates" Similar Words
Antifascist
Antifascist refers to someone or something that opposes fascism, a political ideology characterized by authoritarianism, nationalism, and the suppression of opposition. Antifascists often work to counteract or protest against fascist or far-right activities and ideologies.
Antifebrile
Antifebrile refers to a substance or medication that is used to reduce fever. It helps in lowering body temperature when it is elevated, typically during an illness.
Antifebrin
"Antifebrin" is an old term for a medication or substance used to reduce fever. It refers to drugs that have antipyretic properties, which means they help in lowering body temperature when it rises due to fever. The term is historical and not commonly used today; modern equivalents would be medications like aspirin, paracetamol (acetaminophen), or ibuprofen, which all have fever-reducing capabilities.
Antifeminist
Antifeminist refers to a person who opposes or is against the principles and goals of feminism, which seeks gender equality and the empowerment of women. They may argue that feminist ideas undermine traditional values, gender roles, or they disagree with certain feminist policies or movements.
Antifibrinolytic
Antifibrinolytic refers to a substance or medication that prevents or slows down the breakdown of fibrin, a protein involved in blood clotting. These drugs are used to stop or reduce excessive bleeding by inhibiting the action of enzymes that dissolve blood clots (fibrinolysis). Examples include tranexamic acid and epsilon-aminocaproic acid.
Antiflammatory
Antiflammatory refers to something that reduces inflammation or counters the effects of inflammation. It can be a medication, substance, or treatment that helps alleviate swelling, redness, heat, and pain typically associated with inflammation.
Antiflatulent
Antiflatulent refers to a substance or medication that helps to prevent or relieve flatulence, which is the excessive accumulation of gas in the digestive system, leading to discomfort or bloating. It can also refer to a property of certain foods or remedies that aid in reducing gas build-up.
Antifolate
"Antifolate" refers to a type of medication or substance that inhibits the action of folic acid, which is a B vitamin essential for cell growth and multiplication. Antifolates are used primarily as antimetabolites in cancer therapy to interfere with cancer cell replication, and also as antimalarial drugs. They can block the normal metabolic processes of cells that require folic acid, thus disrupting their ability to divide and grow. Examples of antifolate drugs include methotrexate and pyrimethamine.
Antiform
Antifoulant
Antifouling
Antifreeze
Antifungal
Antifungals
Antigen
Antigene