"Aminoacylation" Pronounce,Meaning And Examples
"Aminoacylation" Natural Recordings by Native Speakers
"Aminoacylation" Meaning
Aminoacylation is the process of attaching an amino acid to its corresponding transfer RNA (tRNA) molecule, forming an aminoacyl-tRNA complex. This process is essential in protein synthesis, as it ensures that the correct amino acids are brought together to build proteins according to the genetic code. The enzyme responsible for this reaction is called aminoacyl-tRNA synthetase.
"Aminoacylation" Examples
1. The process of aminoacylation involves attaching an amino acid to its corresponding tRNA, which is a crucial step in protein synthesis.
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- In the ribosome, aminoacylation ensures that the correct sequence of amino acids is added to the growing polypeptide chain.
2. During translation, the enzyme aminoacyl-tRNA synthetase catalyzes the aminoacylation of tRNA molecules, linking them to their specific amino acids.
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- Each aminoacyl-tRNA synthetase has a high degree of specificity, preventing errors in the aminoacylation process and maintaining the fidelity of protein synthesis.
3. The misincorporation of amino acids due to improper aminoacylation can lead to faulty proteins and various cellular disorders, including some genetic diseases.
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- Researchers are studying how mutations affecting aminoacylation enzymes can contribute to neurodegenerative diseases like Alzheimer's or Parkinson's.
4. The efficiency of aminoacylation affects the overall speed of protein production and can impact cellular responses to stress or environmental changes.
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- Cells regulate the activity of aminoacyl-tRNA synthetases to optimize aminoacylation rates under different conditions, such as during rapid growth or when facing pathogens.
5. In biotechnology, scientists have harnessed aminoacylation for the synthesis of peptide-based drugs, allowing them to create customized therapeutic molecules.
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- Synthetic peptides with modified amino termini via aminoacylation can exhibit improved stability, pharmacokinetics, and target specificity compared to conventional peptides.
"Aminoacylation" Similar Words
Amindivi
The word "Amindivi" refers to an island group in the Union Territory of Lakshadweep, India. It is part of the Amindivi Islands, which are located in the Arabian Sea. The name "Amindivi" is derived from the main island called Aminidivi or Amini. These islands are known for their natural beauty, coral reefs, and marine life.
Amine
Amine: A compound derived from ammonia (NH3) or a nitrogenous organic compound, containing one or more amino (-NH2) groups. Amines can be basic in nature and are involved in various chemical reactions, such as the formation of proteins and other biomolecules. They are also used in the synthesis of pharmaceuticals, dyes, and other industrial products.
Aminergic
Aminergic refers to a group of neurotransmitters or drugs that are derived from amino acids and function in the nervous system. These neurotransmitters, such as serotonin, dopamine, and norepinephrine, play a crucial role in various physiological processes, including mood regulation, movement control, and cognitive function.
Amines
Amines are organic compounds derived from ammonia (NH3) where one or more hydrogen atoms have been replaced by alkyl or aryl groups. They are characterized by the presence of a nitrogen atom bonded to one or more carbon atoms and can exist as primary, secondary, or tertiary amines depending on the number of carbon atoms attached to the nitrogen. Amines have various applications, including use as pharmaceuticals, dyes, solvents, and as building blocks in the synthesis of other organic compounds.
Amino-cyclitols
Amino-cyclitols are a group of compounds that consist of a cyclitol, which is a sugar-like alcohol with a cyclic structure, bearing one or more amino groups (NH2) attached to its carbon skeleton. These compounds can be found in various natural sources and have shown potential biological activities, such as antimicrobial, antiviral, and antioxidant properties. They are also of interest in pharmaceutical and biochemical research due to their unique chemical structures and potential applications in drug development.
Amino-levulinic
Amino-levulinic acid is an organic compound that plays a role in the biosynthesis of porphyrins, which are essential components of heme and chlorophyll. It is derived from the amino acid glycine and is involved in the metabolic pathway known as porphyrin metabolism. This compound is also used in medical tests to diagnose and monitor certain liver and blood disorders.
Amino
Amino refers to amino acids, which are organic compounds that combine to form proteins. They are essential for various biological functions and serve as building blocks of life.
Aminoacyl
Aminoacyl refers to a compound that combines an amino acid with a cytidine diphosphate (CDP) or a similar molecule. It is involved in the process of protein synthesis, where amino acids are attached to transfer RNA (tRNA) molecules, forming aminoacyl-tRNA. This process, called aminoacylation, is essential for translating genetic information from mRNA into proteins.
Aminoalkane
Aminobenzene
Aminobenzoic
Aminobisphosphonates
Aminobutanoic
Aminobutyric
Aminocaproic
Aminocyclitols